Lineups not announcedLineups only · full preview is a separate page

Cleveland Guardians vs Minnesota Twins Starting Lineups — September 21, 2025

Batting orders, positions, season stats, splits against the opposing starter's hand and batter-versus-pitcher history with sample size for both clubs.

2:10 PM ET · Target FieldLineups not confirmedStats updating

Cleveland Guardians

75–73 · 2nd AL Central

Pending

StarterTBD

HandTBD

Minnesota Twins

69–78 · 3rd AL Central

Pending

StarterTBD

HandTBD

Both lineups pending

Neither club has announced a batting order yet. Check back closer to first pitch.