Arizona Diamondbacks at Cincinnati Reds (2026-06-12). Eduardo Rodriguez vs Nick Lodolo at Great American Ball Park.

Eduardo Rodriguez has maintained a strong season with a 2.52 ERA and 1.18 WHIP over 78.2 innings, supported by a 6.52 K/9 and 3.09 BB/9, and his trend ERA is down. While generally effective, his last five starts show some fluctuation, with two outings allowing four earned runs each, contrasting with three prior scoreless appearances. Nick Lodolo, in comparison, features a higher 5.51 ERA and 1.50 WHIP across 32.2 innings, marked by a 3.86 BB/9 and an upward trend in his ERA. Lodolo's recent performance has been inconsistent, yielding 4, 5, 3, 1, and 3 earned runs in his last five starts, highlighting struggles with command and run prevention. Rodriguez presents a more reliable starting option based on his season-long efficiency and overall metrics.

The Arizona Diamondbacks offense has produced 289 runs with a .239 average and a .692 OPS. Their pitching staff collectively holds a 4.28 ERA and 1.28 WHIP. The Cincinnati Reds offense has scored 286 runs, featuring a slightly higher .708 OPS and 85 home runs, though with a lower .231 average and more strikeouts. On the mound, the Reds' team ERA is 4.79 and their WHIP is 1.47, indicating a less effective unit compared to Arizona. Arizona possesses a more efficient pitching staff, while Cincinnati shows a modest offensive edge in power output.

Recent head-to-head matchups from 2025 saw the Cincinnati Reds win five of seven contests against the Diamondbacks, with several games featuring elevated run totals including 10-1 and 13-1. The total line for this game is set at 9.5, which is consistent with the historical tendency for higher scoring games at Great American Ball Park and reflects Nick Lodolo's recent struggles. However, Eduardo Rodriguez's strong season-long effectiveness could challenge this expectation, potentially guiding the game towards a lower overall score if he pitches to his average.

Ketel Marte is 1-for-3 against Nick Lodolo, posting a 1.666 OPS. Ildemaro Vargas has a .250 average, going 2-for-8 with an .875 OPS, while Geraldo Perdomo is 1-for-3 with a 1.666 OPS. Nolan Arenado is hitless in 5 at-bats, going 0-for-5 with a .000 OPS, and Gabriel Moreno is 0-for-2 with a .000 OPS. Corbin Carroll, Player 691783, LuJames Groover, and Ryan Waldschmidt all have no MLB history versus the left-handed Lodolo.

JJ Bleday is 2-for-4 against Eduardo Rodriguez, holding a .500 average and 1.000 OPS. Noelvi Marte is 1-for-2 with a .500 average and 1.000 OPS, and Matt McLain is also 1-for-2 with a .500 average and 1.000 OPS. Spencer Steer is 1-for-5 with a .200 average and .400 OPS. Eugenio Suárez is 1-for-8 in 10 PA against Rodriguez, posting a .125 average and .425 OPS. Dane Myers is 0-for-5 in 6 PA with a .167 OPS, and Tyler Stephenson is 0-for-3 with a .000 OPS. Sal Stewart and Blake Dunn have no MLB history versus Rodriguez.

The home team's lineup features more batters with prior MLB history against their opposing starter compared to the away team.